The Quran teaches that Jesus was conceived by the Spirit of Allah, which shows that He is a special creation of God.

The Quran does speak of Allah breathing His Spirit into Mary, suggesting a miraculous conception. However, this account differs from the Christian narrative where the Holy Spirit is explicitly identified as the agent of conception, emphasizing Jesus' divine nature. In the Gospel of Matthew, it is stated that Mary was found to be with child through the Holy Spirit, indicating that Jesus is not merely a special creation but the eternal Word made flesh (John 1:14). The Quran's portrayal may reflect a misunderstanding of this theological concept. Furthermore, the Quranic verses imply that the Spirit appeared as a man to inform Mary of her pregnancy, which contrasts with the biblical account where an angel delivers the message. This distinction highlights a significant difference in the understanding of Jesus' nature and His relationship with God. The Christian doctrine of the Trinity, which includes the Holy Spirit as fully God, is not present in the Islamic view, leading to different interpretations of Jesus' conception. Ultimately, while both texts acknowledge a miraculous birth, the Christian perspective asserts that Jesus is the preexistent Son of God, fully divine and fully human, a truth that is foundational to Christian faith and not captured in the Quran's narrative.