Muslims might argue that the suffering servant in Isaiah cannot refer to Jesus because he was not a servant of God who suffered for the sins of others.

The passage in Isaiah 53 describes a servant who suffers for the transgressions of others, which aligns closely with the narrative of Jesus' crucifixion and atonement. This servant is depicted as being despised and rejected, bearing the griefs and sorrows of many, which is precisely how Jesus is portrayed in the Gospels. Furthermore, the New Testament writers, such as in Luke 22:37 and John 12:37-41, directly quote Isaiah to illustrate that Jesus fulfills this prophetic role. The fulfillment of these prophecies is not merely coincidental; it is a central theme of the New Testament that emphasizes Jesus as the Messiah who came to save humanity through his suffering and sacrifice. Therefore, the interpretation of Isaiah 53 as referring to Jesus is not only valid but foundational to Christian belief.